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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
POLR3A
All Species:
17.27
Human Site:
S608
Identified Species:
38
UniProt:
O14802
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14802
NP_008986.2
1390
155641
S608
F
S
V
I
L
R
P
S
D
D
N
P
V
R
A
Chimpanzee
Pan troglodytes
XP_507865
1349
150791
S567
F
S
V
I
L
R
P
S
D
D
N
P
V
R
A
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_536399
1390
155706
S608
F
S
V
I
L
R
P
S
D
D
N
P
V
R
A
Cat
Felis silvestris
Mouse
Mus musculus
P08775
1970
217158
G598
I
F
S
L
I
I
P
G
H
I
N
C
I
R
T
Rat
Rattus norvegicus
O54889
1716
194174
G714
Y
T
P
L
N
L
T
G
K
A
K
I
G
S
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514706
1382
154562
S600
F
S
L
I
L
R
P
S
D
A
S
P
V
R
A
Chicken
Gallus gallus
Q5ZL98
1390
155685
S608
F
S
S
I
L
K
P
S
D
D
C
P
V
K
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P04052
1887
209150
G590
I
F
S
L
I
I
P
G
N
V
N
M
I
R
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P16356
1852
203961
G588
V
F
S
L
I
I
P
G
N
V
N
V
L
R
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P18616
1840
204671
L595
T
G
K
Q
V
F
N
L
I
I
P
K
Q
I
N
Baker's Yeast
Sacchar. cerevisiae
P04051
1460
162283
V622
K
P
N
H
N
S
P
V
V
I
N
L
D
A
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.5
N.A.
98.8
N.A.
26
26.8
N.A.
95.9
96.2
N.A.
N.A.
N.A.
27.4
N.A.
27.8
N.A.
Protein Similarity:
100
96.6
N.A.
99.5
N.A.
40.8
43.9
N.A.
98.1
98.5
N.A.
N.A.
N.A.
43.1
N.A.
43.9
N.A.
P-Site Identity:
100
100
N.A.
100
N.A.
20
0
N.A.
80
73.3
N.A.
N.A.
N.A.
20
N.A.
20
N.A.
P-Site Similarity:
100
100
N.A.
100
N.A.
40
20
N.A.
93.3
86.6
N.A.
N.A.
N.A.
46.6
N.A.
46.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
28.7
51.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.9
68.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
19
0
0
0
10
46
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
10
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
46
37
0
0
10
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
46
28
0
0
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
0
0
0
37
0
0
0
0
10
0
0
% G
% His:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
19
0
0
46
28
28
0
0
10
28
0
10
19
10
0
% I
% Lys:
10
0
10
0
0
10
0
0
10
0
10
10
0
10
19
% K
% Leu:
0
0
10
37
46
10
0
10
0
0
0
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% M
% Asn:
0
0
10
0
19
0
10
0
19
0
64
0
0
0
10
% N
% Pro:
0
10
10
0
0
0
82
0
0
0
10
46
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
0
0
37
0
0
0
0
0
0
0
64
0
% R
% Ser:
0
46
37
0
0
10
0
46
0
0
10
0
0
10
0
% S
% Thr:
10
10
0
0
0
0
10
0
0
0
0
0
0
0
28
% T
% Val:
10
0
28
0
10
0
0
10
10
19
0
10
46
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _